Histone acetyltransferase MYST3 (KAT6A) Rabbit Polyclonal Antibody

CAT#: TA360931

KAT6A Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: MYST3 Sample Tissue: Human Jurkat Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MYST3
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 89 kDa
• Gene Name: lysine acetyltransferase 6A
• Database Link:
  NP_006757.2
  Entrez Gene 7994 Human
  UniProt ID A5PLL3
• Background: This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with an autosomal dominant form of cognitive disability. Chromosomal translocations of this gene are associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants.
• Synonyms: 1500036M03; 9930021N24Rik; MOZ; Moz; Myst3; Runxbp2; Zfp220; Znf220