CEP290 Rabbit Polyclonal Antibody

CAT#: TA361098

CEP290 Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: CEP290 Sample Tissue: Human Jurkat Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CEP290
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 88 kDa
• Gene Name: centrosomal protein 290
• Database Link:
  NP_079390.3
  Entrez Gene 80184 Human
  UniProt ID Q05BJ6
• Background: This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.
• Synonyms: 3H11AG; BBS14; CT87; FLJ13615; FLJ21979; JBTS5; JBTS6; KIAA0373; LCA10; MKS4; Nephrocystin-6; nephrocytsin-6; NPHP6; rd16; SLSN6