epithelial Sodium Channel alpha (SCNN1A) Rabbit Polyclonal Antibody

CAT#: TA361270

SCNN1A Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: SCNN1A Sample Tissue: Human Leiomyosarcoma Tumor lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SCNN1A
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 26 kDa
• Gene Name: sodium channel epithelial 1 alpha subunit
• Database Link:
  NP_001029.1
  Entrez Gene 6337 Human
  UniProt ID P37088-3
• Background: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Synonyms: Alpha-ENaC; Alpha-NaCH; BESC2; ENaCa; ENaCalpha; FLJ21883; SCNEA; SCNN1