ZWILCH Rabbit Polyclonal Antibody

CAT#: TA361511

ZWILCH Antibody - middle region

Product Images

Host: Rabbit Target Name: ZWILCH Sample Tissue: Human 786-0 Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ZWILCH
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 65 kDa
• Gene Name: zwilch kinetochore protein
• Database Link:
  NP_001274750.1
  Entrez Gene 55055 Human
  UniProt ID Q9H900
• Background: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex (PubMed:15824131).
• Synonyms: FLJ10036; FLJ16343; hZwilch; KNTC1AP; MGC111034