EXD2 Rabbit Polyclonal Antibody

CAT#: TA362425

EXD2 Antibody - middle region

Product Images

Host: Rabbit Target Name: EXD2 Sample Tissue: Human Jurkat Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle terminal region of human EXD2
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 54 kDa
• Gene Name: exonuclease 3'-5' domain containing 2
• Database Link:
  NP_001180289.1
  Entrez Gene 55218 Human
  UniProt ID Q9NVH0-2
• Background: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
• Synonyms: C14orf114; DKFZp781A0133; DKFZp781L15100; EXDL2; FLJ10738; OTTHUMP00000205813; OTTHUMP00000205816; OTTHUMP00000205817; OTTHUMP00000205818