MPRIP Rabbit Polyclonal Antibody

CAT#: TA362456

MPRIP Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: MPRIP Sample Tissue: Human Jurkat Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MPRIP
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 110 kDa
• Gene Name: myosin phosphatase Rho interacting protein
• Database Link:
  NP_055949.2
  Entrez Gene 23164 Human
  UniProt ID Q6WCQ1-3
• Background: Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
• Synonyms: KIAA0864; M-RIP; MRIP; p116Rip; RHOIP3; RIP3