Neuropilin 1 (NRP1) Rabbit Polyclonal Antibody

CAT#: TA362531

NRP1 Antibody - middle region

Product Images

Host: Rabbit Target Name: NRP1 Sample Tissue: Human Mesenchymoma Tumor lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NRP1
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 70 kDa
• Gene Name: neuropilin 1
• Database Link:
  NP_001019799.1
  Entrez Gene 8829 Human
  UniProt ID O14786-2
• Background: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
• Synonyms: BDCA4; CD304; DKFZp686A03134; DKFZp781F1414; neuropilin-1; NP1; NRP; OTTHUMP00000020818; VEGF165R