PGC1 beta (PPARGC1B) Rabbit Polyclonal Antibody

CAT#: TA362737

PPARGC1B Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: PPARGC1B Sample Tissue: Human THP-1 Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPARGC1B
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 112 kDa
• Gene Name: PPARG coactivator 1 beta
• Database Link:
  NP_001166169.1
  Entrez Gene 133522 Human
  UniProt ID Q86YN6
• Background: The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.
• Synonyms: ERRL1; PERC; PGC-1(beta); PGC-1-beta; PGC1; PGC1B; PPARGC-1-beta; PPARGC1