Cdc20 Rabbit Polyclonal Antibody

CAT#: TA362928

CDC20 Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: CDC20 Sample Tissue: Mouse Stomach lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse CDC20
• Specificity: Expected reactivity: Mouse
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 54 kDa
• Gene Name: cell division cycle 20
• Database Link:
  NP_075712.2
  Entrez Gene 107995 Mouse
  UniProt ID Q9JJ66
• Background: Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.
• Synonyms: bA276H19.3; CDC20A; MGC102824; OTTHUMP00000008572; p55CDC