Wwox Rabbit Polyclonal Antibody

CAT#: TA363010

WWOX Antibody - middle region

Product Images

Host: Rabbit Target Name: WWOX Sample Tissue: Mouse Lung lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse WWOX
• Specificity: Expected reactivity: Mouse
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 45 kDa
• Gene Name: WW domain-containing oxidoreductase
• Database Link:
  NP_062519.2
  Entrez Gene 80707 Mouse
  UniProt ID Q91WL8
• Background: Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm (By similarity). May also play a role in tumor necrosis factor (TNF)-mediated cell death. Required for normal bone development.
• Synonyms: D16S432E; FOR; FRA16D; HHCMA56; PRO0128; SDR41C1; WOX1