Parp2 Rabbit Polyclonal Antibody

CAT#: TA363054

PARP2 Antibody - middle region

Product Images

Host: Rabbit Target Name: PARP2 Sample Tissue: Mouse Brain lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse PARP2
• Specificity: Expected reactivity: Mouse
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 61 kDa
• Gene Name: poly (ADP-ribose) polymerase family, member 2
• Database Link:
  NP_033762.1
  UniProt ID O88554
• Background: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Mediates serine ADP-ribosylation of target proteins following interaction with HPF1; HPF1 conferring serine specificity (By similarity).
• Synonyms: ADPRT2; ADPRTL2; ADPRTL3; hPARP-2; pADPRT-2; PARP-2