Fxn Rabbit Polyclonal Antibody

CAT#: TA363060

FXN Antibody - middle region

Product Images

Host: Rabbit Target Name: FXN Sample Tissue: Mouse Liver lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse FXN
• Specificity: Expected reactivity: Mouse
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 23 kDa
• Gene Name: frataxin
• Database Link:
  NP_032070.1
  UniProt ID O35943
• Background: Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+Â to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+Â to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Modulates the RNA-binding activity of ACO1 (By similarity).
• Synonyms: CyaY; FA; FARR; frataxin; FRDA; MGC57199; X25