Metabotropic Glutamate Receptor 5 (GRM5) Rabbit Polyclonal Antibody

CAT#: TA363650

GRM5 Antibody - middle region

Product Images

Host: Rabbit Target Name: GRM5 Sample Tissue: Human PC-3 Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GRM5
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 133 kDa
• Gene Name: glutamate metabotropic receptor 5
• Database Link:
  NP_000833.1
  Entrez Gene 2915 Human
  UniProt ID P41594
• Background: This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.
• Synonyms: GPRC1E; mGlu5; MGLUR5; OTTHUMP00000165953; OTTHUMP00000165957