AKR1C4 Rabbit Polyclonal Antibody

CAT#: TA363770

AKR1C4 Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: AKR1C4 Sample Tissue: Human LN18 Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1C4
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 35 kDa
• Gene Name: aldo-keto reductase family 1, member C4
• Database Link:
  NP_001809.3
  Entrez Gene 1109 Human
  UniProt ID P17516
• Background: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
• Synonyms: 3-alpha-HSD; 3-alpha-HSD1; C11; CDR; CHDR; DD-4; DD4; HAKRA; MGC22581; OTTHUMP00000018997