CD5 Mouse Monoclonal Antibody [Clone ID: CRIS-1]

CAT#: TA363837

CD5 (T cell antigen T1,Tp67), mouse anti human, clone CRIS-1

Product Images

TA363837, Clone CRIS-1, human tonsil, frozen section

Specifications

Product Data

• Clone Name: CRIS-1
• Applications: IHC
• Recommended Dilution: Tested for immunohistochemistry (IHC); has been described to work in FACS. Approximate working dilution for IHC: Frozen sections: ≤0.1µg/ml (1:2000) Paraffin sections: not tested Optimal dilutions should be determined by the end user. Suggested positive control: Human tonsil
• Reactivities: Human
• Host: Mouse
• Clonality: Monoclonal
• Immunogen: Stimulated human leukocytes.
• Specificity: Human: CD5 Other: not tested.
  
  Epitope: The antigen is CD5. The epitope has not been further characterized.
  
  Distribution: Isolated cells: the antibody stains approximately 50-90% of human peripheral blood mononuclear cells in flow cytometry. Tissue sections: the antibody reacts with the interfollicular area and mantle zone in tonsil.
• Formulation: Affinity purified, lyophilized Reconstitute by adding 0.5ml distilled water. This stock solution contains 0.2mg/ml IgG, phosphate buffered saline pH 7.2 (PBS), 5mg/ml bovine serum albumin (BSA), and 0.09% sodium azide as a preservative.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: 1 year at 4° - 8°C. Stock solution or aliquots thereof: 1 year at -20°C. Avoid repeated thawing and freezing.
• Gene Name: CD5 molecule
• Database Link:
  Entrez Gene 921 Human
  UniProt ID P06127
• Background: Monoclonal antibody CRIS-1 recognizes the human CD5 antigen. CD5 is expressed at low density early on thymocytes and at high density on all mature T lymphocytes. CD5 is expressed at low density on a small subset of mature B lymphocytes (B1a cells) which is expanded during fetal life and in several autoimmune disorders as well as in some B cell- derived lymphoproliferative disorders (chronic lymphocytic leukemia, CLL). CD5 is a glycoprotein monomer of 67kD which belongs to the scavenger receptor cysteine- rich (SRCR) family of extracellular domain-like structures and possesses a large cytoplasmic domain suitable for signal transduction
• Synonyms: LEU1; T1