Cd200 Rat Monoclonal Antibody [Clone ID: OX-90]

CAT#: TA363845

CD200 (OX-2 Antigen), rat anti mouse, clone OX-90


USD 470.00

2 Weeks*

Size
    • 200 ug

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Specifications

Product Data
Clone Name OX-90
Applications ELISA, IHC
Recommended Dilution Tested for immunohistochemistry (IHC); has been described to work in FACS and ELISA.. Approximate working dilution for IHC: Frozen sections: 0.5µg/ml (1:800) Paraffin sections: does not react on routinely processed paraffin sections. Optimal dilutions should be determined by the end user. Suggested positive control: Mouse spleen.
Reactivities Mouse
Host Rat
Isotype IgG2a
Clonality Monoclonal
Immunogen Recombinant mouse CD200 (extracellular region)-rat CD4 (domains 3 & 4) fusion protein.
Specificity Mouse: CD200 positive cells Other species: not tested

Epitope: The epitope has not been further characterized.

Distribution: Tissue Sections: The antigen is expressed on CD200 positive cells including thymocytes, some T cells, endothelial and follicular dendritic cells, and brain tissue (neurons).
Formulation Affinity purified, lyophilized Reconstitute by adding 0.5ml distilled water. This stock solution contains 0.4mg/ml IgG, phosphate buffered saline pH 7.2 (PBS), 5mg/ml bovine serum albumin (BSA) as a stabilizer and 0.09% sodium azide as a preservative.
Concentration N/A
Conjugation Unconjugated
Storage Original vial: 1 year at 4° - 8°C. Stock solution or aliquots thereof: 1 year at -20°C. Avoid repeated thawing and freezing.
Gene Name CD200 antigen
Background Monoclonal antibody OX-90 reacts with CD200 (OX-2 antigen), a type-1 membrane glycoprotein containing two extracellular Ig-like domains. The molecular weight of the OX-2 antigen is 41 to 47kDa. CD200 is expressed on thymocytes, neurons, B lymphocytes, splenic follicular dendritic cells and endothelium, and subsets of T lymphocytes and dendritic cells: The antigen is not expressed on NK cells, granulocytes, monocytes or macrophages. The CD200 receptor is restricted to myeloid cells, and it is believed that its engagement with CD200 results in the activation of anti-inflammatory pathways and the induction of immune tolerance.
Synonyms CD200R1; MOX1; MOX2; MOX2R; MRC; OX-2; OX2R
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.