Kininogen 1 (KNG1) Rabbit Polyclonal Antibody

CAT#: TA363888

Bradykinin; neat antiserum

Product Images

Typical titration curve of Bradykinin in a competitive ELISA with this antibody

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against Bradykinin. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human, Mammalian
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH coupled to a carrier protein.
• Formulation: Neat undiluted antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 50µl distilled water. This will give the equivalent of undiluted antiserum.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Gene Name: kininogen 1
• Database Link:
  Entrez Gene 3827 Human
  UniProt ID P01042
• Background: Bradykinin is a 9 amino acid, biologically active peptide within the kinin group of proteins that promotes inflammation. During inflammation, it is released locally from mast cells and basophils following tissue damage. It has been shown to sensitize capsaicin / temperature TRPV1 receptors, thus lowering the temperature threshold at which they activate. This antibody was generated by immunization of rabbits with Bradykinin coupled to a carrier protein.
• Synonyms: BDK; bradykinin; HMWK; kininogen; KNG