Endothelin 1 (EDN1) Rabbit Polyclonal Antibody

CAT#: TA363914

Endothelin-1 (hu, bo, ca, ms, po, rt); diluted antiserum


USD 690.00

2 Weeks*

Size
    • 500 Tests

Product Images

Other products for "EDN1"

Specifications

Product Data
Applications ELISA
Recommended Dilution This antibody has been tested and validated in ELISA against Endothelin-1 and in immunohistochemistry (IHC). Other applications like FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivities Human, Bovine, Dog, Mouse, Porcine, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide H-Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys- Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-OH (Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11) coupled to carrier protein.
Formulation This polyclonal antibody is supplied as a lyophilized powder. The powder should be rehydrated with 50ml of RIA buffer. Upon reconstitution to 50ml total volume, the solution contains 0.1M sodium phosphate buffer (pH 7.4), 0.05M NaCl, 0.1% BSA, 0.01% NaN3, and 0.1% Triton X-100. Store at 4° - 8°C. This should ensure antibody stability for approximately one month.
Concentration N/A
Conjugation Unconjugated
Storage Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Gene Name endothelin 1
Background Endothelin-1 is a potent vasoconstrictor produced by vascular endothelial cells. It plays an important role in regulation of cardiovascular functions. The binding of Endothelin-1 to its G-protein coupled receptor triggers a signal transduction cascade leading to activation of the protein kinase C (PKC). PKC inhibitor potentially reverses the up-regulation of Endothelin-1. The enhanced Endothelin-1 expression associated with the activation of PKC occurs in early diabetes. This antibody was generated by immunization of rabbits with Endothelin-1 coupled to a carrier protein.
Synonyms ET1; HDLCQ7; PPET1; Preproendothelin-1
Reference Data

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.