Leuprolide Rabbit Polyclonal Antibody

CAT#: TA363927

(Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH (Leuprolide); neat antiserum

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against Leuprolide. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human, Mammalian
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide Pyr-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt coupled to carrier protein.
• Formulation: Neat undiluted antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 50µl distilled water. This will give the equivalent of undiluted antiserum.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Background: Leuprolide is a synthetic nonapeptide analogue of gonadrotropin-releasing hormone, used to treat prostate cancer, breast cancer, endometriosis, uterine fibroids, and early puberty. Leuprolide binds to and activates gonadotropin-releasing hormone (GnRH) receptors. Agonism of GnRH receptors initially results in the stimulation of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion by the anterior pituitary ultimately leading to increased serum estradiol and testosterone levels via the normal physiology of the hypothalamic–pituitary–gonadal axis. This antibody was generated by immunization of rabbits with Leuprolide coupled to a carrier protein.