Insulin (INS) Rabbit Polyclonal Antibody

CAT#: TA364023

Rabbit polyclonal anti C-Peptide (hu); purified rabbit IgG

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against C-peptide. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide H-Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu- Leu- Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu- Glu-Gly-Ser- Leu-Gln-OH coupled to a carrier protein.
• Formulation: Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Gene Name: insulin
• Database Link:
  Entrez Gene 3630 Human
  UniProt ID P01308
• Background: The connecting peptide, or C-peptide of human proinsulin, is a 31-amino-acid polypeptide that connects insulin's A-chain to its B-chain. In the context of diabetes or hypoglycemia, a measurement of C-peptide blood serum levels can be used to distinguish between different conditions with similar clinical features. In normal tissues, the antigen is found in pancreaticislet β-cells. C-peptide has been found to be a bioactive peptide in its own right, with effectson microvascular blood flow and tissue health. This antibody was generated by immunization of rabbits with C-peptide coupled to a carrier protein.
• Synonyms: ILPR; insulin; IRDN; OTTHUMP00000011162; OTTHUMP00000196038; proinsulin