Calcitonin (CALCA) Rabbit Polyclonal Antibody

CAT#: TA364040

Rabbit polyclonal anti human Calcitonin Gene-Related Peptide 1 (alpha-CGRP)

Product Images

Typical titration curve of Calcitonin in a competitive ELISA with this antibody

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against Calcitonin. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide H-Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr-Tyr- Thr-Gln-Asp-Phe-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ala-Ile-Gly-Val- Gly-Ala-Pro-NH2, (Disulfide bond) coupled to carrier protein.
• Formulation: Neat undiluted antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 50µl distilled water. This will give the equivalent of undiluted antiserum.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Gene Name: calcitonin related polypeptide alpha
• Database Link:
  Entrez Gene 796 Human
  UniProt ID P06881
• Background: Calcitonin gene-related peptide (CGRP) is a member of the calcitonin family of peptides, which in human exists in two forms: α-CGRP and β-CGRP. α-CGRP, also known as CGRP I, is a 37-amino acid regulatory neuropeptide formed from the alternative splicing of the calcitonin/CGRP gene located on chromosome 11. While, β-CGRP differs from α-CGRP by three amino acids and is encoded in a separate gene within the same vicinity. α-CGRP is widely distributed in the central and peripheral nervous system and it is known to be the most potent vasodilator with inotropic and chronotropic effects. This antibody was generated by immunization of rabbits with Calcitonin coupled to a carrier protein.
• Synonyms: CALC1; CGRP; CGRP-I; CGRP1; CT; katacalcin; KC; MGC126648; PCT; Procalcitonin