Calcitonin (CALCA) Rabbit Polyclonal Antibody

CAT#: TA364043

Rabbit polyclonal anti human Calcitonin Gene-Related Peptide 1 (alpha-CGRP)

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against α-CGRP. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide H-Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu- Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val- Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2, (Disulfide bond) coupled to carrier protein.
• Formulation: Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Gene Name: calcitonin related polypeptide alpha
• Database Link:
  Entrez Gene 796 Human
  UniProt ID P06881
• Background: α-Calcitonin Gene-Related Peptide (α-CGRP) is a regulatory neuropeptide of 37 amino acids and is formed by the alternative splicing of the calcitonin / CGRP gene located on chromosome 11. It is widely distributed in both the peripheral and central nervous system, predominantly in cell bodies of the dorsal root ganglion (DRG) and it is known to be a potent vasodilator with inotropic and chronotropic effects. This antibody was generated by immunization of rabbits with α-Calcitonin Gene- Related Peptide coupled to a carrier protein.
• Synonyms: CALC1; CGRP; CGRP-I; CGRP1; CT; katacalcin; KC; MGC126648; PCT; Procalcitonin