Delta-Sleep Inducing Peptide Rabbit Polyclonal Antibody

CAT#: TA364049

Rabbit polyclonal anti Delta-Sleep Inducing Peptide; purified rabbit IgG

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against Delta- sleep-inducing peptide. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human, Mammalian
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-NH2 coupled to a carrier protein.
• Formulation: Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Background: Delta-sleep-inducing peptide (DSIP) is an amphiphilic neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities. It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids. In the pituitary, it co-localizes with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH). Delta-sleep-inducing peptide is abundant in the gut secretory cells and in the pancreas where it co-localizes with glucagon. It functions in endocrine regulation and in physiological processes. This antibody was generated by immunization of rabbits with Delta-sleep-inducing peptide coupled to a carrier protein.