IGF1 Rabbit Polyclonal Antibody

CAT#: TA364120

Rabbit polyclonal anti rec IGF-I (hu); diluted antiserum

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against IGF-I. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide H-Gly-Pro-Glu-Thr-Leu-Cys-Gly-Ala-Glu-Leu-Val-Val- Asp-Ala-Leu-Gln-Phe-Val-Cys-Gly-Asp-Arg-Gly-Phe-Tyr-Phe-Asn-Lys- Pro-Thr-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-Gly-Ile-Val- Asp-Glu-Cys-Cys-Phe-Arg-Ser-Cys-Asp-Leu-Arg-Arg-Leu-Glu-Met-Tyr- Cys-Ala-Pro-Leu-Lys-Pro-Ala-Lys-Ser-Ala (disulfide bond) coupled to carrier protein.
• Formulation: Each vial contains enough antiserum for 500 RIA tubes. The powder should be rehydrated with 50ml RIA buffer. Upon reconstitution to 50ml total volume, the solution contains 0.1M sodium phosphate buffer (pH 7.4), 0.05M NaCl, 0.1% BSA, 0.01% NaN3, and 0.1% Triton X-100. Store at 4°C. This should ensure antibody stability for approximately one month.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Gene Name: insulin like growth factor 1
• Database Link:
  Entrez Gene 3479 Human
  UniProt ID P05019
• Background: Insulin-like Growth Factor I (IGF-I), also known as Somatomedin C, is a hormone similar to insulin. It is produced primarily by the liver as an endocrine hormone, which effects a wide range of cells and plays a key role in cell proliferation and growth. IGF- I is also linked with tumor cell growth, due to its inhibitory effect on apoptosis. This antibody was generated by immunization of rabbits with IGF-I coupled to a carrier protein.
• Synonyms: IBP1; IGF-1; IGF-IA; IGF-IB; IGF1A; IGFI; MGF; OTTHUMP00000195084; Somatomedin-C