GnRH (GNRH1) Rabbit Polyclonal Antibody

CAT#: TA364144

Rabbit polyclonal anti LHRH; purified rabbit IgG

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against Luteinizing Hormone-Releasing Hormone. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human, Mammalian
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 coupled to carrier protein.
• Formulation: Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Gene Name: gonadotropin releasing hormone 1
• Database Link:
  Entrez Gene 2796 Human
  UniProt ID P01148
• Background: Luteinizing hormone-releasing hormone (LHRH), also known as Gonadotropin-Releasing Hormone (GnRH) or Luteinizing Hormone-Releasing Factor (LRF), is a hypothalamic neuropeptide which acts on the pituitary to stimulate the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). LHRH may act as a growth modulatory factor in tumors of the reproductive system. The effects of LHRH are mediated by high-affinity G protein-coupled LHRH-receptor (LHRH-R) on pituitary gonadotropes. HRH and LHRH receptors (LHRH-Rs) are expressed in human melanoma cells and LHRH-Rs are found in more than 50% of human breast cancers. This antibody was generated by immunization of rabbits with Luteinizing Hormone-Releasing Hormone coupled to a carrier protein.
• Synonyms: GNRH; GRH; LHRH; LNRH