ACTH (POMC) Rabbit Polyclonal Antibody

CAT#: TA364148

Alpha-Melanocyte-Stimulating Hormone (alpha-MSH), rabbit anti alpha-MSH

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against α-MSH. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human, Mammalian
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys- Pro-Val-NH2 coupled to a carrier protein.
• Formulation: Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Gene Name: proopiomelanocortin
• Database Link:
  Entrez Gene 5443 Human
  UniProt ID P01189
• Background: Alpha-Melanocyte Stimulating Hormone (α-MSH) belongs to a group of peptide hormones also known as melanotropins. α-MSH is a neuropeptide derived from proopiomelanocortin (POMC) which is expressed in the pituitary gland and belongs to the melanocortin family. It is well known in stimulating melanin synthesis (melanogenesis) as well as in feeding behavior and energy homeostasis. Recently, it has been found that α-MSH affects immune reactions in the host for controlling inflammation in the brain and peripheral organs. This antibody was generated by immunization of rabbits with α-MSH coupled to a carrier protein.
• Synonyms: ACTH; adrenocorticotropin; alpha-MSH; beta-endorphin; beta-LPH; beta-MSH; CLIP; Corticotropin-lipotropin; gamma-LPH; gamma-MSH; LPH; met-enkephalin; MSH; NPP; OTTHUMP00000119991; OTTHUMP00000200964; POC; pro-ACTH-endorphin; proopiomelanocortin