PACAP (ADCYAP1) Rabbit Polyclonal Antibody

CAT#: TA364168

Rabbit polyclonal anti PACAP-27 (hu, ms, ov, po, rt); neat antiserum

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against PACAP- 27. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human, Mouse, Porcine, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg- Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH₂ coupled to carrier protein.
• Formulation: Neat undiluted antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 50µl distilled water. This will give the equivalent of undiluted antiserum; does not contain any preservative.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Gene Name: adenylate cyclase activating polypeptide 1
• Database Link:
  Entrez Gene 116 Human
  UniProt ID P18509
• Background: Pituitary adenylate cyclase-activating polypeptide (PACAP) and Vasoactive Intestinal Peptide (VIP), as well as the three classes of G-protein-coupled receptors mediating their effects, are widely distributed in the central nervous system (CNS) and peripheral tissues. These peptides are reported to have many physiological or pharmacological effects in different tissues. Particularly important are their roles in glucose metabolism and on islets; their anti- inflammatory, cytoprotective effects, their CNS neuroprotective effects, and their possible roles in diseases such as schizophrenia and chronic depression. PACAP-27 is the 27 amino acid peptide cleaved off the full-length PACAP. This antibody was generated by immunization of rabbits with PACAP-27 coupled to a carrier protein.
• Synonyms: MGC126852; OTTHUMP00000162201; PACAP