Chga Rabbit Polyclonal Antibody

CAT#: TA364183

Rabbit polyclonal anti Pancreastatin (1-51) (rt); purified rabbit IgG

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against Pancreastatin (1-51) / Chromogranin-A (264-314). Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Rat
• Host: Rabbit
• Clonality: Polyclonal
• Formulation: Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Gene Name: chromogranin A
• Database Link:
  Entrez Gene 24258 Rat
  UniProt ID P10354
• Background: Pancreastatin is a 49 amino acid peptide found in many cells of the neuroendocrine system. It is produced from the proteolytic cleavage of its precursor, Chromogranin A [Chromogranin A (240-288)]. It is localized to insulin-containing beta cells, glucagon- containing alpha cells, and somatostatin-containing D cells of the pancreatic islet. Pancreastatin inhibits release of somatostatin upon glucose stimulation and it may also control carbohydrate metabolism and hyperglycemia. This antibody was generated by immunization of rabbits with Pancreastatin (1-51) / Chromogranin-A (264-314) coupled to a carrier protein.
• Synonyms: CgA; SP-I