Parathyroid Hormone (PTH) Rabbit Polyclonal Antibody

CAT#: TA364194

Rabbit polyclonal anti pTH (1-38) (hu); neat antiserum

Product Images

Typical titration curve of pTH (1-34) in a competitive ELISA with this antibody

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against pTH 1-38. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly- Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu- Gln-Asp-Val-His-Asn-Phe-Val-Ala-Leu-Gly-OH coupled to carrier protein.
• Formulation: Neat undiluted antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 50µl distilled water. This will give the equivalent of undiluted antiserum.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Gene Name: parathyroid hormone
• Database Link:
  Entrez Gene 5741 Human
  UniProt ID P01270
• Background: Parathyroid hormone (pTH) is secreted by the parathyroid glands as a polypeptide containing 84 amino acids. It acts to increase the concentration of calcium in the blood, whereas calcitonin acts to decrease calcium concentration. PTH acts to increase the concentration of calcium in the blood by acting upon parathyroid hormone receptor in three parts of the body as well as stimulates bone formation in both animals and humans. PTH 1-38 stimulates the expression of UBP41, an ubiquitin-specific protease, important to maintain bone homeostasis. This antibody was generated by immunization of rabbits with pTH 1-38 coupled to a carrier protein.
• Synonyms: parathormone; Parathyrin; PTH1