Tgfa Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | ELISA |
Recommended Dilution | This antibody has been tested and validated in ELISA against TGF-α (1- 50). Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user. |
Reactivities | Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide H-Val-Val-Ser-His-Phe-Asn-Asp-Cys-Pro-Asp-Ser-His- Thr-Gln-Phe-Cys-Phe-His-Gly-Thr-Cys-Arg-Phe-Leu-Val-Gln-Glu-Asp- Lys-Pro-Ala-Cys-Val-Cys-His-Ser-Gly-Tyr-Val-Gly-Ala-Arg-Cys-Glu-His- Ala-Asp-Leu-Leu-Ala-OH coupled to carrier protein. |
Formulation | Neat undiluted antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 50µl distilled water. This will give the equivalent of undiluted antiserum. |
Concentration | N/A |
Conjugation | Unconjugated |
Storage | Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below. |
Gene Name | transforming growth factor alpha |
Database Link | |
Background | Transforming Growth Factor-alpha (TGF-α), also known as sarcoma growth factor, TGF-type I and ETGF, is a member of the EGF family of cytokines. It is expressed in monocytes, brain cells, keratinocytes and various tumor cells. TGF-α signals through EGFR and acts synergistically with TGF-beta to promote the proliferation of a wide range of epidermal and epithelial cells. TGF-α is a transforming growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. The biological actions of TGF-α and EGF are similar. This antibody was generated by immunization of rabbits with TGF-α (1-50) coupled to a carrier protein. |
Synonyms | TFGA |
Reference Data |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.