ProDynorphin (PDYN) Rabbit Polyclonal Antibody

CAT#: TA364238

Rabbit polyclonal anti a-Neoendorphin; diluted antiserum

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against α- Neoendorphin. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human, Mammalian
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide H-Tyr-Gly-Gly-Phe-Leu-Arg-Lys-Tyr-Pro-Lys-OH coupled to carrier protein.
• Formulation: This polyclonal antibody is supplied as a lyophilized powder. The powder should be rehydrated with 50ml of RIA buffer. Upon reconstitution to 50ml total volume, the solution contains 0.1M sodium phosphate buffer (pH 7.4), 0.05M NaCl, 0.1% BSA, 0.01% NaN3, and 0.1% Triton X-100. Store at 4° - 8°C. This should ensure antibody stability for approximately one month.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Gene Name: prodynorphin
• Database Link:
  Entrez Gene 5173 Human
  UniProt ID P01213
• Background: α-Neoendorphin is an endogenous opioid neuropeptide with a decapeptide structure. It is derived from the proteolytic cleavage of prodynorphin. Some studies revealed that α- Neoendorphin immunoreactive fibers throughout the human brainstem and it can be found in the caudal part of the solitary nucleus, in the caudal and the gelatinosa parts of the spinal trigeminal nucleus, and in the central grey matter of medulla. This antibody was generated by immunization of rabbits with α-Neoendorphin coupled to a carrier protein.
• Synonyms: beta-neoendorphin; beta-neoendorphin-dynorphin; dynorphin; leu-enkephalin; leumorphin; MGC26418; PENKB; preprodynorphin; prodynorphin; rimorphin