Cortistatin (CORT) Rabbit Polyclonal Antibody

CAT#: TA364285

Rabbit polyclonal anti Cortistatin-17 (hu); diluted antiserum

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against Cortistatin-17. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide H-Asp-Arg-Met-Pro-Cys-Arg-Asn-Phe-Phe-Trp-Lys- Thr-Phe-Ser-Ser-Cys-Lys-OH coupled to carrier protein.
• Formulation: Each vial contains enough antiserum for 500 RIA tubes. The powder should be rehydrated with 50ml RIA buffer. Upon reconstitution to 50ml total volume, the solution contains 0.1M sodium phosphate buffer (pH 7.4), 0.05M NaCl, 0.1% BSA, 0.01% NaN3, and 0.1% Triton X-100. Store at 4°C. This should ensure antibody stability for approximately one month.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Gene Name: cortistatin
• Database Link:
  Entrez Gene 1325 Human
  UniProt ID O00230
• Background: The 105 amino acid residue human precortistatin in turn is cleaved into cortistatin-17 and cortistatin-29. Cortistatin-17 is the only active peptide derived from the precursor. It is a neuropeptide that is expressed in inhibitory neurons of the cerebral cortex, and which has a strong structural similarity to somatostatin. Unlike somatostatin, when infused into the brain, it enhances slow-wave sleep. It binds to sites in the cortex, hippocampus and the amygdala. This antibody was generated by immunization of rabbits with Cortistatin-17 coupled to a carrier protein.
• Synonyms: cortistatin; cortistatin-14; cortistatin-17; cortistatin-29; CST-14; CST-17; CST-29; MGC32686; preprocortistatin