Cortistatin (CORT) Rabbit Polyclonal Antibody

CAT#: TA364292

Rabbit polyclonal anti Cortistatin-17 (hu); purified rabbit IgG

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against Cortistatin-17. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide H-Asp-Arg-Met-Pro-Cys-Arg-Asn-Phe-Phe-Trp-Lys- Thr-Phe-Ser-Ser-Cys-Lys-OH coupled to a carrier protein.
• Formulation: Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Gene Name: cortistatin
• Database Link:
  Entrez Gene 1325 Human
  UniProt ID O00230
• Background: The 105 amino acid residue human precortistatin in turn is cleaved into cortistatin-17 and cortistatin-29. Cortistatin-17 is the only active peptide derived from the precursor. It is a neuropeptide that is expressed in inhibitory neurons of the cerebral cortex, and which has a strong structural similarity to somatostatin. Unlike somatostatin, when infused into the brain, it enhances slow-wave sleep. It binds to sites in the cortex, hippocampus and the amygdala. This antibody was generated by immunization of rabbits with Cortistatin-17 coupled to a carrier protein.
• Synonyms: cortistatin; cortistatin-14; cortistatin-17; cortistatin-29; CST-14; CST-17; CST-29; MGC32686; preprocortistatin