GLP1 (GCG) Rabbit Polyclonal Antibody

CAT#: TA364300

Rabbit polyclonal anti Oxyntomodulin (glucagon-37) (hu, ms, rt); neat antiserum

Product Images

Typical titration curve of Oxyntomodulin in a competitive ELISA with this antibody

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against Oxyntomodulin. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys- Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn- Thr-Lys-Arg-Asn-Arg-Asn-Asn-Ile-Ala-OH coupled to carrier protein.
• Formulation: Neat undiluted antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 50µl distilled water. This will give the equivalent of undiluted antiserum.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Gene Name: glucagon
• Database Link:
  Entrez Gene 2641 Human
  UniProt ID P01275
• Background: Oxyntomodulin (OXM) a 37-amino acid peptide hormone found in the colon, produced by the oxyntic cells of the oxyntic mucosa. It is known to suppress appetite and causes weight loss in humans and rodents. Oxyntomodulin activates both the glucagon-like peptide-1 receptor (GLP1R) and the glucagon receptor (GCGR). It contains the same sequence as Glucagon (1-29), but with an additional KRNKNNIA C-terminal sequence. This antibody was generated by immunization of rabbits with Oxyntomodulin coupled to a carrier protein.
• Synonyms: GLP1; GLP2; glucagon; GRPP