Exendin-4 Rabbit Polyclonal Antibody

CAT#: TA364338

Rabbit polyclonal anti Exendin-4, purified IgG

Specifications

Product Data

• Applications: ELISA
• Recommended Dilution: This antibody has been tested and validated in ELISA against Exendin- 4. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
• Reactivities: Human, Mammalian
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys- Gln-Met-Glu-GluGlu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly- Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 coupled to a carrier protein.
• Formulation: Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
• Concentration: N/A
• Conjugation: Unconjugated
• Storage: Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
• Background: Exendin-4 is a 39 amino acid peptide amide known to be a long-acting agonist of the glucagon-like peptide 1 receptor (GLP-1). It is involved in glucose-dependent enhancement of insulin secretion, reduction of hyperglycemia, and glucose- dependent suppression of high glucagon secretion. Exendin-4 is used as active component of Byetta® (exenatide) injection, which may improve glycemic control in people with type 2 diabetes mellitus. This antibody was generated by immunization of rabbits with Exendin-4 coupled to a carrier protein.