Tat-Beclin-1 Rabbit Polyclonal Antibody

CAT#: TA364358

Rabbit polyclonal anti Tat-Beclin-1 (267-284); purified rabbit IgG


USD 655.00

2 Weeks*

Size
    • 400 ug

Product Images

Other products for "Tat-Beclin-1"

Specifications

Product Data
Applications ELISA
Recommended Dilution This antibody has been tested and validated in ELISA against Tat- Beclin-1. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly- Gly-Thr-Asn-Val-Phe-Asn-Ala-Thr-Phe-Glu-Ile-Trp-His-Asp-Gly-Glu-Phe- Gly-Thr-OH coupled to a carrier protein.
Formulation Protein A affinity purified from antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 0.2ml distilled water. This stock solution contains 2mg/ml IgG, phosphate buffer saline pH 7.4 (PBS), and 0.02% (w/v) Thimerosal as a preservative.
Concentration N/A
Conjugation Unconjugated
Storage Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Background The Tat-Beclin-1 (autophagy activator) peptide is derived from a region of the autophagy protein, beclin 1, attached to the HIV-1 Tat protein transduction domain. The peptide includes 11 amino acids at the N terminus derived from the Tat protein transduction domain, 18 amino acids (267–284 aa) from beclin 1 at the C terminus and a GG linker. It reduces the accumulation of polyglutamine aggregates and pathogen replication in vitro. Tat-Beclin-1 is also found to reduce the mortality of mice infected by different viruses as well as is predicted to stimulate cell death via autophagy. This antibody was generated by immunization of rabbits with Tat-Beclin-1 coupled to a carrier protein.
Reference Data

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.