COX7B2 Rabbit Polyclonal Antibody

CAT#: TA364411

COX7B2 rabbit polyclonal antibody

Product Images

Immunohistochemistry of paraffin-embedded Human lymphoma tissue using TA364411 (COX7B2 Antibody) at dilution 1/15 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lymphoma tissue using TA364411 (COX7B2 Antibody) at dilution 1/15, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: IHC: 15-50
  Positive control: Human lymphoma
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human COX7B2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Database Link:
  UniProt ID Q8TF08
• Background: The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. COX7b (cytochrome c oxidase subunit VIIb polypeptide) and COX7b2 (cytochrome c oxidase subunit VIIb polypeptide 2) are 80 and 81 amino acid proteins, respectively, which exist as components of the COX complex, therefore playing an important role in electron transport. A rare polymorphism in the COX7b2 gene at codon 26 may be linked to nasopharyngeal carcinoma (NPC), the most common head and neck cancer in southern China.