BUD31 Rabbit Polyclonal Antibody

CAT#: TA365539

BUD31 rabbit polyclonal antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane 1-6: Raji 231 and PC-3 cell Mouse heart tissue Mouse brain tissue Human testis tissue lysates Primary antibody: TA365539 (BUD31 Antibody) at dilution 1/450 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA365539 (BUD31 Antibody) at dilution 1/45 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA365539 (BUD31 Antibody) at dilution 1/45, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA365539 (BUD31 Antibody) at dilution 1/45 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA365539 (BUD31 Antibody) at dilution 1/45, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Raji，231 and PC-3 cell，Mouse heart tissue，Mouse brain tissue，Human testis tissue lysates
  IHC: 30-150
  Positive control: Human ovarian cancer
  Predicted cell location: Cytoplasm and Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Full length fusion protein
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 17 kDa
• Database Link:
  UniProt ID P41223
• Background: BUD31 (Protein G10 homolog, EDG-2) is a 144 amino acid protein encoded by the human gene BUD31. BUD31 is a nuclear protein that belongs to the BUD31 (G10) family. BUD31 is found on chromosome 7 which is about 158 milllion bases long, encodes over 1,000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to osteogenesis imperfecta, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the long (q) arm of human chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.