TXNL1 Rabbit Polyclonal Antibody

CAT#: TA366003

TXNL1 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-5: Mouse fetal liver tissue Mouse brain tissue HepG2 cell HUVEC cell PC-3 cell lysates Primary antibody: TA366003 (TXNL1 Antibody) at dilution 1/1300 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 10 seconds

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA366003 (TXNL1 Antibody) at dilution 1/60 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA366003 (TXNL1 Antibody) at dilution 1/60, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA366003 (TXNL1 Antibody) at dilution 1/60 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA366003 (TXNL1 Antibody) at dilution 1/60, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: Mouse fetal liver tissue, Mouse brain tissue, HepG2 cell, HUVEC cell, PC-3 cell lysates
  IHC: 50-200
  Positive control: Human esophagus cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human TXNL1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 32 kDa
• Database Link:
  UniProt ID O43396
• Background: TXNL1(Thioredoxin-like protein 1) is also named as TRP32, TXL, TXNL and belongs to the thioredoxin family. It might be involved in the cellular response to sugar starvation stress. The predicted 289-amino acid, 32.3-kD protein has 2 distinct domains: an N-terminal domain, which is 43% identical to human TXN, and a C-terminal domain, which showed no homology to other proteins in the sequence databases. TXNL1 functions as an effector of oxidants or redox sensor that couples oxidative stress to endocytosis, by converting redox changes into a specific GDI:Rab5-mediated endocytic response.