MDFI Rabbit Polyclonal Antibody
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Other products for "MDFI"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB: 500-2000 WB positive control: Human placenta tissue lysate IHC: 50-300 Positive control: Human esophagus cancer Predicted cell location: Nucleus |
Reactivities | Human, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein of human MDFI |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C. |
Stability | 1 year |
Predicted Protein Size | 25 kDa |
Database Link | |
Background | This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. |
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in shipping.