ING1 Rabbit Polyclonal Antibody

CAT#: TA371129

ING1 rabbit polyclonal antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 100-500
  WB positive control: Mouse brain tissue and Jurkat cells, Raw264.7 and hepG2 cells
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human ING1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 47 kDa
• Database Link:
  UniProt ID Q9UK53
• Background: This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.