n-Myc (MYCN) Rabbit Polyclonal Antibody
Other products for "MYCN"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 500-2000 WB positive control: Hela cell lysate |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human MYCN |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C. |
Stability | 1 year |
Predicted Protein Size | 50 kDa |
Gene Name | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
Database Link | |
Background | This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Synonyms | bHLHe37; MODED; N-myc; NMYC; ODED; pp65/67 |
Reference Data |
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