PDPN Rabbit Polyclonal Antibody

CAT#: TA371618

PDPN rabbit polyclonal antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane 1-3: Human fetal brain tissue Hela cells 293T cells Primary antibody: TA371618 (PDPN Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 5 minutes

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA371618 (PDPN Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA371618 (PDPN Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human fetal brain tissue, Hela and 293T cells
  IHC: 10-50
  Positive control: Human liver cancer
  Predicted cell location: Cell membrane
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human PDPN
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 17 kDa; 25 kDa
• Gene Name: podoplanin
• Database Link:
  Entrez Gene 10630 Human
  UniProt ID Q86YL7
• Background: This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Synonyms: aggrus; GP36; Gp38; GP40; HT1A-1; hT1alpha-1; hT1alpha-2; OTS8; PA2.26; podoplanin; T1-alpha; T1A; T1A-2