XPC Rabbit Polyclonal Antibody

CAT#: TA371625

XPC rabbit polyclonal antibody


USD 380.00

4 Weeks*

Size
    • 100 ul

Product Images

Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 20-100
Positive control: Human tonsil
Predicted cell location: Cytoplasm or Nucleus
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human XPC
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C.
Stability 1 year
Gene Name XPC complex subunit, DNA damage recognition and repair factor
Background The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
Synonyms p125; RAD4; XP3; XPCC
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.