CHURC 1 (CHURC1) Rabbit Polyclonal Antibody

CAT#: TA372238

CHURC1 rabbit polyclonal antibody

Product Images

Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA372238 (CHURC1 Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA372238 (CHURC1 Antibody) at dilution 1/25, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA372238 (CHURC1 Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA372238 (CHURC1 Antibody) at dilution 1/25, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human ovarian cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human CHURC1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Gene Name: churchill domain containing 1
• Database Link:
  Entrez Gene 91612 Human
  UniProt ID Q8WUH1
• Background: CHURC1, also known as protein Churchill, is a 112 amino acid protein that plays a critical role in neural induction during embryogenesis. The fibroblast growth family of proteins (FGFs) has been identified as necessary factors in mesoderm formation and neural induction. CHURC1, a putative zinc finger protein, is a transcriptional activator that mediates FGF signaling. Furthermore, CHURC1 is thought to play a role in the regulation of cell movement. Although CHURC1 does not bind to DNA, it functions as a transcriptional regulator and a protein-interaction factor. Two isoforms of CHURC1 exist as a result of alternative splicing events.
• Synonyms: C14orf52; chch; FLJ33064; My015