EXD2 Rabbit Polyclonal Antibody
Other products for "EXD2"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 25-100 Positive control: Human cervical cancer Predicted cell location: Nucleus |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human EXD2 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C. |
Stability | 1 year |
Gene Name | exonuclease 3'-5' domain containing 2 |
Database Link | |
Background | Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks. |
Synonyms | C14orf114; DKFZp781A0133; DKFZp781L15100; EXDL2; FLJ10738; OTTHUMP00000205813; OTTHUMP00000205816; OTTHUMP00000205817; OTTHUMP00000205818 |
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