GTF3C4 Rabbit Polyclonal Antibody

CAT#: TA372700

GTF3C4 rabbit polyclonal antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane 1-4: A172 Hela Jurkat and Raji cell lysates Primary antibody: TA372700 (GTF3C4 Antibody) at dilution 1/1300 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 2 minutes

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA372700 (GTF3C4 Antibody) at dilution 1/160 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA372700 (GTF3C4 Antibody) at dilution 1/160, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: A172, Hela, Jurkat and Raji cell lysates
  IHC: 150-300
  Positive control: Human esophagus cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human GTF3C4
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 92 kDa
• Gene Name: general transcription factor IIIC subunit 4
• Database Link:
  Entrez Gene 9329 Human
  UniProt ID Q9UKN8
• Background: Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.
• Synonyms: FLJ21002; KAT12; MGC138450; TF3C-delta; TFIII90; TFIIIC90; TFIIIC290; TFIIICDELTA