CYP11B1 Rabbit Polyclonal Antibody

CAT#: TA372999

CYP11B1 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-4: Mouse heart tissue Mouse kidney tissue 293T cell Mouse liver tissue lysates Primary antibody: TA372999 (CYP11B1 Antibody) at dilution 1/500 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 1 minute

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Mouse heart tissue, Mouse kidney tissue, 293T cell, Mouse liver tissue lysates
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human CYP11B1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 58 kDa
• Gene Name: cytochrome P450 family 11 subfamily B member 1
• Database Link:
  Entrez Gene 1584 Human
  UniProt ID P15538
• Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.
• Synonyms: CPN1; CYP11B; CYPXIB1; DKFZp686B05283; FHI; FLJ36771; P-450c11; P450C11; S11BH