ABCA1 Rabbit Polyclonal Antibody

CAT#: TA373063

ABCA1 rabbit polyclonal antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane 1-2: Human bladder transitional cell carcinoma grade 2-3 tissue Human bladder transitional cell carcinoma cancer next level 2-3 tissue lysates Primary antibody: TA373063 (ABCA1 Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 1 minute

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human bladder transitional cell carcinoma grade 2-3 tissue, Human bladder transitional cell carcinoma cancer next level 2-3 tissue lysates
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human ABCA1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 254 kDa
• Gene Name: ATP binding cassette subfamily A member 1
• Database Link:
  Entrez Gene 19 Human
  UniProt ID O95477
• Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.
• Synonyms: ABC-1; ABC1; CERP; FLJ14958; HDLDT1; membrane-bound; MGC164864; MGC165011; TGD