ATP citrate lyase (ACLY) Rabbit Polyclonal Antibody

CAT#: TA373194

Phospho-ACLY-S455 Rabbit polyclonal Antibody


USD 355.00

3 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC, IP, WB
Recommended Dilution WB,1:500 - 1:2000
IHC,1:50 - 1:100
IP,1:50 - 1:100
Reactivities Human, Mouse, Rat
Modifications Phospho S455
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A synthetic phosphorylated peptide around S455 of human ACLY (NP_001087.2).
Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Store at -20℃. Avoid freeze / thaw cycles.
Stability Shelf life: one year from despatch.
Predicted Protein Size 91kDa/119kDa/120kDa
Gene Name ATP citrate lyase
Background ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.